Introduction: Androgenetic alopecia (AGA) is one of the three common forms of noncicatricialalopecia characterized by hair loss and constitutes 95% of alopecias in both women and men. Of men in their 50s, 50% display various degrees of AGA. Two effective treatment methods for AGA are usedin men: topical minoxidil and systematic finasteride. Clinical studies have shown that minoxidil and finasteride have well-known therapeutic effects against AGA.
Purpose: This study was conducted to compare the reliability and effectiveness of “topical Redensyl, Capixyl, and Procapil (RCP)” combination (Hair 360) and “topical minoxidil 5%” in adult male patients suffering from AGA.
Materials and Method: This study randomized patients to use either a serum containing topical RCP or only topical minoxidil 5% for 24 weeks. The patients applied 1 mL of each solution onto the affected zone of hair skin twice per day.
Findings: Comparison of the RCP (Hair 360 men spray) and minoxidil groups showed that patients in the topical RCP group achieved more recovery, which was statically significant according to the researcher evaluation (RCP: 65%; minoxidil: 26%), global photographic assessment (RCP: 89%; minoxidil: 60%), and self-assessment questionnaire.
Result: This study indicated that topical RCP formulation achieved clinically significant recovery and was significantly more effectivecompared with topical minoxidil regardinghair growth and thickness.
Recovery results after 9- to 10-month use were as follows: